Horror crash leaves girl dead, police shaken

A TEENAGER has died in a horror road accident in Brisbane's bayside - a family trip to Christmas lunch ending in another tragedy on Queensland's roads.

The 18-year-old woman was sitting in the back seat of the family sedan when an out-of-control car crashed through the median strip on Manly Rd at Manly West and hit her car head-on at high speed.

Horror crash leaves girl dead, police shaken

The horror crash on Manly Rd at Manly West. (AAP image, John Gass)

A black BMW knocked down a tree as it crossed on to the wrong side of the busy road and crashed into the ­silver sedan.

First responders performed CPR and tried to revive the woman but she was declared dead at the scene.

A 56-year-old woman - the front seat passenger of the silver sedan - is fighting for her life in hospital.

Horror crash leaves girl dead, police shaken

Police at the scene of a fatal car crash at Manly West. Picture: AAP/John Gass

A 23-year-old woman, who was driving the car, is in a serious condition, as is the 55-year-old male back seat passenger.

The 46-year-old driver of the black BMW is also in a serious condition.

The dramatic crash occurred in front of families celebrating Christmas and prompted police to close Manly Rd for several hours during the afternoon.

Witnesses said police officers appeared shaken by the horrific scene.

A doctor stopped to render medical assistance to those involved, and police have since asked her to contact them.

Horror crash leaves girl dead, police shaken

Emergency services on Manly Rd.

So far this year 243 people have lost their lives on the state's roads.

More than 3100 Queenslanders have been hospitalised as a result of a serious road accident so far in 2017 - that is about 100 more people than at the same time last year.

With Boxing Day expected to be one of the busiest travel days of the year, police are warning motorists to be careful on the road.

Assistant Commissioner Mike Keating said police are targeting high-risk road user behaviour including speeding, drinking and drug driving, distracted driving, fatigue and failing to wear a seatbelt.

Mr Keating said that fatigue caused almost 10 per cent of fatalities in Queensland this year.